Target discovery

Target identification, validation and prioritization using a user-friendly platform

The problem

Drug development pipelines suffer from increasings costs and declining success rates. More than half of the failures can be explained by lack of efficacy, of which almost half can be explained by poor linkage between target and disease. Selecting better targets can double the success rate of the drug development pipeline.

How The Hyve can help

The Open Targets Platform is an open-source web-based platform, that integrates multiple data sources of various types. It features a scoring algorithm on target-disease associations to help you to identify, validate and prioritize drug targets for further research. The Open Targets Genetics Platform allows you to discover associations between genes, variants and traits, and integrates well with the Open Targets Platform.

We help our clients by supporting these tools and are working with two of the Open Targets consortium partners to implement them within their organization. In addition, three other pharma companies, outside of the consortium, have expressed an interest to work with Open Targets in the near future.

Open Targets Open Targets

The Open Targets target validation platform and genetics portal are great tools to support the target discovery process, which is an essential part of the drug discovery pipeline. The Open Targets Platform is an open-source web-based platform, that integrates multiple data sources of various types. The more recently released Open Targets Genetics Platform allows you to discover associations between genes, variants and traits using GWAS data.

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Let's start collaborating

  • The most user-friendly tool for target discovery
  • The best Open Targets specialists
  • Well connected in the Open Targets consortium

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